José Antonio Gandarillas Huici (July 23, 1885 – 1970) was a Chilean diplomat. In the early summer of 1921, José Antonio Gandarillas Huici met painter Christopher Wood. Gandarillas, a married homosexual fourteen years older than Wood, lived a glamorous life partly financed by gambling. Their relationship lasted through Wood's life.

He was the son of José Antonio Gandarillas Luco and Rosa Huici Arguedas. He married Juana Edwards Mac-Clure and was the father of Carmen Gandarillas Edwards; Marie Rose Gandarillas Edwards e Juana Carlota Victoria Gandarillas Edwards.